Nucleofill strong 2.5% 1.5ml Syringe
Nucleofill strong 2.5% 1.5ml Syringe
Description
Nucleofill 25 (Strong) is a bio stimulant gel based on natural polynucleotides and high viscosity for skin rejuvenation and protection. As an anti-ageing treatment. Nucleofill is designed to improve skin elasticity and tightness as well as aid in the prevention of wrinkles. Nucleofill 25 is the new line of natural polynucleotide-based bio stimulating gels, with a high viscosity, for protecting and rejuvenating the skin. It’s recommended to have 2 treatments with 2-4 weeks in between each session, in severe cases you can have up to 4 treatments with 2-4 weeks intervals.
The product contains high molecular weight polynucleotide chains whose biochemical peculiarities make it highly viscoelastic and capable of binding and orient in space a considerable amount of water molecules, which are primarily retained in the hydrophilic groups level of phosphorylated sugars of the individual nucleotides.
The strong moisturising ability is mainly due to the water retention capabilities of the hydrophilic groups of the phosphorylated sugars of the single nucleotides. An “electrostatic sponge” able to guarantee cellular well-being by conferring deep hydration to tissues.
Free radical scavenger effect – The polymeric macromolecules are able to also play an immediate “scavenger” action against free radicals. This effect of this polynucleotide gel is possible thanks to the chemical structure capable of blocking free radicals in the nitrogenous ring. Moreover, the progressive degradation of polynucleotide molecules by enzymes present in the extracellular environment, free metabolites which, in turn, accentuate the protection activity against free radicals.
The biostimulating effect is given both by the presence of nucleoside structures capable of activating cell membrane receptors, and by metabolites that are produced by the enzymatic attack during the degradation process. A slow and continuous effect.
By promoting the metabolic activity of the fibroblastic cells, polynucleotides collaborate to reintegrate into the dermis various fundamental autologous components (glucoseaminoglycans, proteins, glycoproteins, fibrils, etc.) tending to maintain their physiological functionality. Their repeated administration over time, determines:
– a protracted isosmotic hydration of the dermal matrix
– an anti-radical action
Both of these effects combine to recreate in the dermal matrix the most favourable physiological conditions for the regeneration and metabolic activity of fibroblasts, with long-lasting biorevitalising effects.
Polynucleotides activate two types of membrane receptors in fibroblasts, or rather Receptor CD39 and Receptor CD40. The activation of these receptors lead to two effects: stimulation of type I collagen production, saturation of fibroblasts in myofibroblasts
Contains:
25mg/ml of polynucleotides
The synergy of 4 types of stimulation:
– Skin regeneration
– Cleansing effect on the cells by increasing circulation and removing free radicals
– Deep moisturising effect
– Firming and contouring
Indications:
– Loose skin with poor circulation
– Dehydrated skin
– Skin submitted to oxidative stress
– Stretch marks
– Scars
– For those who want firming and contouring, more definition
– Bio-stimulation and increase in collagen type 1.
Related Products and Clinic Supplies
Explore more Nucleofill products or compare our wider Polynucleotides range. Prepare for treatment with Pre-Treatment Supplies, including Needles & Syringes, Gauze & Wipes and Gloves & PPE. Complete the clinic journey with Sharps Disposal and Post-Treatment Essentials.
Delivery & Returns
Dispatch: Orders are dispatched via tracked courier on UK working days.
Returns: Sealed, in-date, unopened items may be returned within 14 days of delivery for a full refund. Contact our team to start a return.
Documentation: Every dispatch includes batch and expiry information suitable for CQC inspection records.
Frequently asked questions
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Who operates Longeva Aesthetics?
Longeva Aesthetics is a trading name of Longeva Limited, a company registered in England and Wales (company number 17217141). We operate as a business-to-business supplier to professional customers from our trading address in Rochdale, Greater Manchester. Full company and contact details are set out in our Legal Notice and Contact policy. -
What documentation do I get with my order?
An itemised order invoice is provided. Product packaging and supplied documentation should be checked for applicable batch, lot, serial and expiry information. Customers remain responsible for retaining records required by their professional, legal and manufacturer obligations. Contact us if you require available supplier documentation. -
How quickly will my order arrive?
Orders are processed and dispatched on UK working days, subject to stock availability, cleared payment and any required checks. We do not publish a guaranteed dispatch cut-off time, and delivery estimates are not guarantees. Available services, charges and estimated delivery windows are shown at checkout. Orders are not sent using a temperature-controlled or cold-chain service. See our Shipping and Delivery Policy for full details. -
Where can I find the terms governing product information and supply?
Product information on this site is general commercial information and does not replace current manufacturer instructions or professional judgement. Customers remain responsible for lawful purchase and use, product suitability, storage, handling and traceability. See our Legal Notice and Terms of Service for the full governing information. -
What is Longeva Aesthetics’ returns policy?
Longeva Aesthetics is a business-to-business supplier. All sales are final once accepted and dispatched, and we do not offer consumer or change-of-mind returns. A return may only be considered for defective, damaged or incorrect goods, a discretionary return we authorise in writing, or where law requires another remedy. Do not send goods back without written return authorisation. See our Returns and Refunds Policy for full eligibility, evidence and reporting requirements.